TMTPOST -- U.S. President Donald Trump signed an executive order Monday establishing the Genesis Mission, a sweeping federal initiative to harness artificial intelligence (AI) for accelerating scientific breakthroughs across critical research domains. Michael Kratsios, the president's science and technology adviser, described it as "the largest marshaling of federal scientific resources since the Apollo program."
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The initiative directs the Department of Energy (DOE) to leverage its national laboratories and supercomputing resources to build an integrated AI platform that will dramatically compress research timelines—from years to potentially days or hours. Energy Secretary Chris Wright will oversee implementation, while Kratsios will coordinate participating agencies through the National Science and Technology Council.
White House officials said partnerships with private-sector companies including Nvidia Corp., Dell Technologies Inc., HPE and Advanced Micro Devices Inc.(AMD) will enhance supercomputing capacity at federal labs, according to Bloomberg. The expansion aims to address challenges spanning biotechnology, nuclear energy, critical materials, semiconductors and space exploration.
The effort seeks to tackle a persistent productivity problem: despite soaring research budgets since the 1990s, scientific progress has stalled with declining drug approvals and diminishing returns on researcher output. Officials predict AI-accelerated workflows will multiply returns on taxpayer investment while strengthening national security and economic competitiveness.
Platform Integration and Computing Resources
The executive order instructs Wright to establish the American Science and Security Platform within his department, consolidating high-performance computing resources, AI modeling frameworks and secure access to federal datasets. The platform will integrate both on-premises supercomputers and cloud-based computing environments capable of supporting large-scale model training.
Within 90 days, the secretary must identify available federal computing, storage and networking resources, including capabilities from industry partners. Within 120 days, the DOE will catalog initial datasets and develop plans for incorporating research data from federal agencies, academic institutions and approved private-sector partners, subject to cybersecurity measures and classification requirements.
The order mandates demonstrating initial operating capability for at least one national science challenge within 270 days. Within 240 days, Wright must review national laboratory capabilities for robotic laboratories and AI-directed experimentation, including automated workflows.
Priority Research Domains
The Energy Department has 60 days to identify at least 20 science and technology challenges of national importance that could benefit from the Mission. Kratsios will then coordinate development of an expanded list through participating agencies, focusing on advanced manufacturing, biotechnology, critical materials, nuclear fission and fusion energy, quantum information science, and semiconductors and microelectronics.
"By fusing massive federal data sets, advanced supercomputing capabilities, and world-leading scientific facilities, the Genesis mission will use AI to automate experiment design, accelerate simulation and generate protective models for everything from protein folding to fusion plasma dynamics," Kratsios told reporters, according to CBS News.
The initiative targets practical applications including materials engineering, health sciences and disease therapies. Officials emphasized the effort would help boost production and lower prices, addressing voter concerns about living costs.
Public-Private Partnerships and Energy Concerns
The order establishes mechanisms for agency collaboration with external partners possessing advanced AI, data or computing capabilities. Wright must develop standardized partnership frameworks, including cooperative research agreements and data-sharing arrangements, while implementing stringent cybersecurity standards for non-federal collaborators.
The secretary will establish policies governing intellectual property ownership, licensing and commercialization of innovations arising from AI-directed experiments. Vetting procedures will ensure authorized access to platform resources and federal research facilities.
Wright addressed concerns about AI's energy demands on Monday, stating the Genesis initiative would help counter rising electricity costs. "We're going to stop the rise of price of energy. First, it'll plateau, and ultimately will push downward pressure on the prices of electricity," he said.
The Mission builds on existing infrastructure including the National Artificial Intelligence Research Resource pilot program, which connects federal agencies ranging from the Department of Defense to the National Institutes of Health with non-governmental partners.
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